Tolerability and safety of urotainer® polihexanide 0.02% in catheterized patients: a prospective cohort study.

ABSTRACT:

Background

In patients with indwelling bladder catheters for > 2 weeks, bacterial colonization is inevitable, leading to urinary tract infections or encrustations with subsequent catheter blockage. Currently, bladder irrigations are the most frequently used prophylactic means, but the best solution remains yet to be determined. In vitro studies demonstrate that polihexanide is a promising option for catheter irrigation, but no data about safety and tolerability exist.

Methods

In a prospective observational study in patients with indwelling bladder catheter for > 2 weeks, a 0.02% polihexanide solution was used to rinse the catheter on five consecutive days. Adverse events, tolerability and vital signs were assessed before, during, after and at the end of the treatment period.

SUBMITTER: Pannek J 

PROVIDER: S-EPMC7346619 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature