Mesenchymal Stem Cells: A New Piece in the Puzzle of COVID-19 Treatment.

ABSTRACT: COVID-19 is a disease characterized by a strong inflammatory response in severe cases, which fails to respond to corticosteroid therapy. In the context of the current COVID-19 outbreak and the critical information gaps regarding the disease, several different therapeutic strategies are under investigation, including the use of stem cells. In the present manuscript, we provide an analysis of the rationale underlying the application of stem cells to manage COVID-19, and also a comprehensive compendium of the 69 clinical trials underway worldwide aiming to investigate the application of stem cells to treat COVID-19. Even though data are still scarce, it is already possible to observe the protagonism of China in testing mesenchymal stem cells (MSCs) for COVID-19. Furthermore, it is possible to

SUBMITTER: Saldanha-Araujo F 

PROVIDER: S-EPMC7347794 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature