Ontology highlight
ABSTRACT:
SUBMITTER: Peille AL
PROVIDER: S-EPMC7347869 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Communications biology 20200709 1
Patient-derived xenografts (PDX) have emerged as an important translational research tool for understanding tumor biology and enabling drug efficacy testing. They are established by transfer of patient tumor into immune compromised mice with the intent of using them as Avatars; operating under the assumption that they closely resemble patient tumors. In this study, we established 27 PDX from 100 resected gastric cancers and studied their fidelity in histological and molecular subtypes. We show t ...[more]