Open software platform for automated analysis of paper-based microfluidic devices.

ABSTRACT: Development of paper-based microfluidic devices that perform colorimetric measurements requires quantitative image analysis. Because the design geometries of paper-based microfluidic devices are not standardized, conventional methods for performing batch measurements of regularly spaced areas of signal intensity, such as those for well plates, cannot be used to quantify signal from most of these devices. To streamline the device development process, we have developed an open-source program called ColorScan that can automatically recognize and measure signal-containing zones from images of devices, regardless of output zone geometry or spatial arrangement. This program, which measures color intensity with the same accuracy as standard manual approaches, can rapidly process scanned device im

SUBMITTER: Parker RW 

PROVIDER: S-EPMC7347888 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature