An Independent Locus Upstream of ASIP Controls Variation in the Shade of the Bay Coat Colour in Horses.

ABSTRACT: Novel coat colour phenotypes often emerge during domestication, and there is strong evidence of genetic selection for the two main genes that control base coat colour in horses-ASIP and MC1R. These genes direct the type of pigment produced, red pheomelanin (MC1R) or black eumelanin (ASIP), as well as the relative concentration and the temporal-spatial distribution of melanin pigment deposits in the skin and hair coat. Here, we describe a genome-wide association study (GWAS) to identify novel genic regions involved in the determination of the shade of bay. In total, 126 horses from five different breeds were ranked according to the extent of the distribution of eumelanin: spanning variation in phenotype from black colour restricted only to the extremities to the

SUBMITTER: Corbin LJ 

PROVIDER: S-EPMC7349280 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature