Family-Specific Gains and Losses of Protein Domains in the Legume and Grass Plant Families.

ABSTRACT: Protein domains can be regarded as sections of protein sequences capable of folding independently and performing specific functions. In addition to amino-acid level changes, protein sequences can also evolve through domain shuffling events such as domain insertion, deletion, or duplication. The evolution of protein domains can be studied by tracking domain changes in a selected set of species with known phylogenetic relationships. Here, we conduct such an analysis by defining domains as "features" or "descriptors," and considering the species (target + outgroup) as instances or data-points in a data matrix. We then look for features (domains) that are significantly different between the target species and the outgroup species. We study the domain changes in 2 large, distinct groups of plan

SUBMITTER: Yadav A 

PROVIDER: S-EPMC7350399 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature