Therapeutic opportunities to manage COVID-19/SARS-CoV-2 infection: Present and future.

ABSTRACT: A severe form of respiratory disease - COVID-19, caused by SARS-CoV-2 infection, has evolved into a pandemic resulting in significant morbidity and mortality. The unabated spread of the disease is due to lack of vaccine and effective therapeutic agents against this novel virus. Hence, the situation demands an immediate need to explore all the plausible therapeutic and prophylactic strategies that can be made available to stem the spread of the disease. Towards this effort, the current review outlines the key aspects of the pathobiology associated with the morbidity and mortality in COVID-19 patients, which includes a viral response phase and an exaggerated host response phase. The review also summarizes therapeutic agents that are currently being explored along with those with potential fo

SUBMITTER: Shetty R 

PROVIDER: S-EPMC7350468 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature