Escher-Trace: a web application for pathway-based visualization of stable isotope tracing data.

ABSTRACT:

Background

Stable isotope tracing has become an invaluable tool for probing the metabolism of biological systems. However, data analysis and visualization from metabolic tracing studies often involve multiple software packages and lack pathway architecture. A deep understanding of the metabolic contexts from such datasets is required for biological interpretation. Currently, there is no single software package that allows researchers to analyze and integrate stable isotope tracing data into annotated or custom-built metabolic networks.

Results

We built a standalone web-based software, Escher-Trace, for analyzing tracing data and communicating results. Escher-Trace allows users to upload baseline corrected mass spectrometer (MS) tracing data and correct for natural isotope ab

SUBMITTER: Kumar A 

PROVIDER: S-EPMC7350651 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature