Osteoporotic fracture rates in chronic hemodialysis and effect of heparin exposure: a retrospective cohort study.

ABSTRACT:

Background

Patients receiving chronic hemodialysis treatments are at a higher risk of fracture compared to the general population. While the use of heparin during dialysis is crucial to avoid thrombosis of the extracorporeal circuit, the association of unfractionated heparin (UFH) and the risk of osteoporotic fracture has been shown for many years. However, this association was not as clear for low-molecular-weight heparin (LMWH) and the few collected data originated from studies among pregnant women. Our aim was to measure osteoporotic fracture rate among hemodialysis patients and to evaluate the association of LMWH compared to UFH in hemodialysis.

Methods

A retrospective cohort study was conducted on data extracted from the RAMQ and Med-Echo databases from January 2007 to

SUBMITTER: Harrak H 

PROVIDER: S-EPMC7350680 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature