GfoRmula: An R Package for Estimating the Effects of Sustained Treatment Strategies via the Parametric g-formula.

ABSTRACT: Researchers are often interested in estimating the causal effects of sustained treatment strategies, i.e., of (hypothetical) interventions involving time-varying treatments. When using observational data, estimating those effects requires adjustment for confounding. However, conventional regression methods cannot appropriately adjust for confounding in the presence of treatment-confounder feedback. In contrast, estimators derived from Robins's g-formula may correctly adjust for confounding even if treatment-confounder feedback exists. The package gfoRmula implements in R one such estimator: the parametric g-formula. This estimator can be used to estimate the effects of binary or continuous time-varying treatments as well as contrasts defined by static or dynamic, deterministic, or random i

SUBMITTER: McGrath S 

PROVIDER: S-EPMC7351102 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature