Longitudinal wastewater sampling in buildings reveals temporal dynamics of metabolites.

ABSTRACT: Direct sampling of building wastewater has the potential to enable "precision public health" observations and interventions. Temporal sampling offers additional dynamic information that can be used to increase the informational content of individual metabolic "features", but few studies have focused on high-resolution sampling. Here, we sampled three spatially close buildings, revealing individual metabolomics features, retention time (rt) and mass-to-charge ratio (mz) pairs, that often possess similar stationary statistical properties, as expected from aggregate sampling. However, the temporal profiles of features-providing orthogonal information to physicochemical properties-illustrate that many possess different feature temporal dynamics (fTDs) across buildings, with large and unpredict

SUBMITTER: Evans ED 

PROVIDER: S-EPMC7351223 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature