Cardiometabolic risk factors as determinants of peripheral nerve function: the Maastricht Study.

ABSTRACT:

Aims/hypothesis

We aimed to examine associations of cardiometabolic risk factors, and (pre)diabetes, with (sensorimotor) peripheral nerve function.

Methods

In 2401 adults (aged 40-75 years) we previously determined fasting glucose, HbA_1c, triacylglycerol, HDL- and LDL-cholesterol, inflammation, waist circumference, blood pressure, smoking, glucose metabolism status (by OGTT) and medication use. Using nerve conduction tests, we measured compound muscle action potential, sensory nerve action potential amplitudes and nerve conduction velocities (NCVs) of the peroneal, tibial and sural nerves. In addition, we measured vibration perception threshold (VPT) of the hallux and assessed neuropathic pain using the DN4 interview. We assessed cross-sectional associations of ri

SUBMITTER: van der Velde JHPM 

PROVIDER: S-EPMC7351845 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature