Neuropsychological development in adolescents: Longitudinal associations with white matter microstructure.

ABSTRACT: Important neuropsychological changes during adolescence coincide with the maturation of white matter microstructure. Few studies have investigated the association between neuropsychological development and white matter maturation longitudinally. We aimed to characterize developmental trajectories of inhibition, planning, emotion recognition and risk-taking and examine whether white matter microstructural characteristics were associated with neuropsychological development above and beyond age. In an accelerated longitudinal cohort design, n = 112 healthy adolescents between ages 9 and 16 underwent cognitive assessment and diffusion MRI over three years. Fractional anisotropy (FA) and mean diffusivity (MD) were extracted for major white matter pathways using an automatic probabilistic recons

SUBMITTER: Murner-Lavanchy IM 

PROVIDER: S-EPMC7352053 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature