Sex Differences and Commonalities in the Impact of a Palatable Meal on Thalamic and Insular Connectivity.

ABSTRACT: The neural mechanisms underlying subjective responses to meal ingestion remain incompletely understood. We previously showed in healthy men an increase in thalamocortical, and a decrease in insular-cortical connectivity in response to a palatable meal. As sex is increasingly recognized as an important biological variable, we aimed to evaluate sex differences and commonalities in the impact of a well-liked meal on thalamic and anterior insular connectivity in healthy individuals. Participants (20 women and 20 age-matched men) underwent resting-state magnetic resonance imaging (rsMRI) before and after ingesting a palatable meal. In general, the insula showed extensive postprandial reductions in connectivity with sensorimotor and prefrontal cortices, while the thalamus showed increases in con

SUBMITTER: Kilpatrick L 

PROVIDER: S-EPMC7352462 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature