Combining clinical and MRI data to manage PI-RADS 3 lesions and reduce excessive biopsy.

ABSTRACT:

Background

Prostate Imaging Reporting and Data System version 2 (PI-RADS V2) 3 category lesions are of intermediate status with an equivocal risk of presenting clinically significant prostate cancer (csPCa). How to avoid excessive biopsies while improving the csPCa detection rate in these lesions has always been a clinical problem that needed to be solved. The purpose of this study is to explore the csPCa diagnostic value of clinical and magnetic resonance imaging (MRI) data for peripheral and transitional zone (PZ and TZ, respectively) PI-RADS 3 lesions to aid in clinical decision-making and reduce excessive biopsies.

Methods

From March 2016 to October 2018, a total of 629 men who underwent a prostate MRI and subsequently biopsy were enrolled. Two radiologists (with 3 and 7

SUBMITTER: Yang S 

PROVIDER: S-EPMC7354292 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature