Associations of maternal phthalate and bisphenol urine concentrations during pregnancy with childhood blood pressure in a population-based prospective cohort study.

ABSTRACT:

Objectives

Fetal exposure to phthalates and bisphenols may lead to vascular developmental adaptations, which program later cardiovascular disease. We examined the associations of fetal exposure to phthalates and bisphenols with childhood blood pressure.

Methods

In a population-based, prospective cohort study among 1,064 mother-child pairs, we measured maternal urine phthalate and bisphenol concentrations in first, second and third trimester of pregnancy. We measured childhood blood pressure at the mean age of 9.7 years (standard deviation 0.2 years) old. Analyses were performed for the total group, and for boys and girls separately.

Results

Maternal urine phthalate concentrations were not associated with childhood blood pressure among boys. Higher third trimester mate

SUBMITTER: Sol CM 

PROVIDER: S-EPMC7354351 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature