Sex differences in flow cytometry-based platelet reactivity in stable outpatients suspected of myocardial ischemia.

ABSTRACT:

Background

Antiplatelet therapy is the mainstay of secondary prevention of cardiovascular events. Studies suggest that women do not obtain equal therapeutic benefit from antiplatelet therapy compared with men. The link between sex differences in platelet biology and response to antiplatelet therapies is unclear. We therefore investigated the role of sex differences in platelet reactivity in a cohort of outpatients with chest pain, in response to treatment with antiplatelet agents.

Methods

Platelet reactivity was measured in 382 randomly selected patients participating in the Myocardial Ischemia Detection by Circulating Biomarkers (MYOMARKER) study, an observational cohort study of outpatients suspected of myocardial ischemia. In all patients, blood was collected during diagn

SUBMITTER: Waissi F 

PROVIDER: S-EPMC7354392 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature