Effectiveness of beta blockers in patients with and without a history of myocardial infarction.

ABSTRACT:

Purpose

Studies demonstrating mortality benefit of beta blockers (BB) after myocardial infarction (MI) were conducted before the era of percutaneous intervention and widespread use of statins. Recent retrospective studies show inconsistent results regarding which subgroups of coronary artery disease (CAD) patients' benefit. Most studies did not account for medication changes over time. We evaluated the association of time-varying BB exposure with death in CAD patients with or without a history of MI.

Methods

This retrospective cohort study included all patients with MI and those with coronary disease but no MI at a single health care system who also had health insurance from January 1, 1997, to June 30, 2011. Pharmacy claims data were used to estimate BB exposure over 6-mont

SUBMITTER: Verma S 

PROVIDER: S-EPMC7354894 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature