Small Circular DNA Molecules as Triangular Scaffolds for the Growth of 3D Single Crystals.

ABSTRACT: DNA is a very useful molecule for the programmed self-assembly of 3D (three dimension) nanoscale structures. The organised 3D DNA assemblies and crystals enable scientists to conduct studies for many applications such as enzymatic catalysis, biological immune analysis and photoactivity. The first self-assembled 3D DNA single crystal was reported by Seeman and his colleagues, based on a rigid triangle tile with the tile side length of two turns. Till today, successful designs of 3D single crystals by means of programmed self-assembly are countable, and still remain as the most challenging task in DNA nanotechnology, due to the highly constrained conditions for rigid tiles and precise packing. We reported here the use of small circular DNA molecules instead of linear ones as the core triangl

SUBMITTER: Wang Y 

PROVIDER: S-EPMC7355631 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature