Association between Active Helicobacter pylori Infection and Glaucoma: A Systematic Review and Meta-Analysis.

ABSTRACT: Background: Glaucoma is the second most common cause of blindness worldwide affecting almost 70 million individuals. Helicobacter pylori (H. pylori) is a widespread pathogen with systematic pathogenicity. This meta-analysis aimed to estimate the contradictory data regarding a potential association between active H. pylori infection and glaucoma. Materials and Methods: A research in MEDLINE/PubMed and Google Scholar was conducted and original studies investigating the relationship between H. pylori infection and glaucoma were included. Analysis was performed with random effects model. The main outcome was the odds ratio (OR) with 95% confidence intervals (CI) of H. pylori infection as a risk factor for glaucoma. A parallel analysis studied the role of active infection as indicated by histol

SUBMITTER: Doulberis M 

PROVIDER: S-EPMC7355761 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature