Pulmonary hypertension with adult respiratory distress syndrome: prevalence, clinical impact, and association with central venous pressure.

ABSTRACT: Pulmonary hypertension (PH) occurs in patients with acute respiratory distress syndrome (ARDS); the most severe form comprises acute cor pulmonale (ACP). Here, we investigated the prevalence of PH in patients with ARDS to evaluate its correlation with ACP risk, ARDS severity and central venous pressure (CVP). We conducted a secondary analysis using data from the MIMIC-III open-source clinical database. The prevalence of PH associated with new-onset ARDS during the first 72 h after intensive care unit admission was investigated; moreover, the association between ACP risk score and PH was validated. We also evaluated the association between elevated CVP (mean CVP > 10 mmHg) and PH and other clinical outcomes. Among 2434 patients who met the ARDS Berlin criteria and underwent echocardiography

SUBMITTER: Li DK 

PROVIDER: S-EPMC7357056 | biostudies-literature | 2020 Jul-Sep

REPOSITORIES: biostudies-literature