Aerobic exercise improves cognition and cerebrovascular regulation in older adults.

ABSTRACT: OBJECTIVE:To test the hypothesis that aerobic exercise is associated with improvements in cognition and cerebrovascular regulation, we enrolled 206 healthy low-active middle-aged and older adults (mean ± SD age 65.9 ± 6.4 years) in a supervised 6-month aerobic exercise intervention and assessed them before and after the intervention. METHODS:The study is a quasi-experimental single group pre/postintervention study. Neuropsychological tests were used to assess cognition before and after the intervention. Transcranial Doppler ultrasound was used to measure cerebral blood flow velocity. Cerebrovascular regulation was assessed at rest, during euoxic hypercapnia, and in response to submaximal exercise. Multiple linear regression was used to examine the association between changes in cognition a

SUBMITTER: Guadagni V 

PROVIDER: S-EPMC7357295 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature