Can Pathogenic and Nonpathogenic Bacteria Be Distinguished by Sensory Protein Abundance?

ABSTRACT: Signal transduction systems are essential for microorganisms to respond to their ever-changing environment. They can be distinguished into one-component systems, two-component systems, and extracytoplasmic-function σ factors. Abundances of a few signal-transducing proteins, termed herein as sensory proteins (SPs), have previously been reported to be correlated with the genome size and ecological niche of certain Gram-positive bacteria. No such reports are available for Gram-negative bacteria. The current study attempts to investigate the relationship of the abundances of SPs to genome size in Escherichia coli, and the bacterial pathotypes or phylotypes. While the relationship between SP abundance and genome size could not be established, the sensory protein index (SPI), a new metric define

SUBMITTER: Bhar S 

PROVIDER: S-EPMC7357476 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature