Functional and cognitive outcomes after COVID-19 delirium.
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ABSTRACT: Purpose
To ascertain delirium prevalence and outcomes in COVID-19.Methods
We conducted a point-prevalence study in a cohort of COVID-19 inpatients at University College Hospital. Delirium was defined by DSM-IV criteria. The primary outcome was all-cause mortality at 4 weeks; secondary outcomes were physical and cognitive function.Results
In 71 patients (mean age 61, 75% men), 31 (42%) had delirium, of which only 12 (39%) had been recognised by the clinical team. At 4 weeks, 20 (28%) had died, 26 (36%) were interviewed by telephone and 21 (30%) remained as inpatients. Physical function was substantially worse in people after delirium - 50 out of 166 points (95% CI - 83 to - 17, p = 0.01). Mean cognitive scores at follow-up were similar and delirium was not associated with mortality in this sample.Conclusions
Our findings indicate that delirium is common, yet under-recognised. Delirium is associated with functional impairments in the medium term.
SUBMITTER: Mcloughlin BC
PROVIDER: S-EPMC7358317 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Publications
Functional and cognitive outcomes after COVID-19 delirium.
Mcloughlin Benjamin C BC Miles Amy A Webb Thomas E TE Knopp Paul P Eyres Clodagh C Fabbri Ambra A Humphries Fiona F Davis Daniel D
European geriatric medicine 20200714 5
<h4>Purpose</h4>To ascertain delirium prevalence and outcomes in COVID-19.<h4>Methods</h4>We conducted a point-prevalence study in a cohort of COVID-19 inpatients at University College Hospital. Delirium was defined by DSM-IV criteria. The primary outcome was all-cause mortality at 4 weeks; secondary outcomes were physical and cognitive function.<h4>Results</h4>In 71 patients (mean age 61, 75% men), 31 (42%) had delirium, of which only 12 (39%) had been recognised by the clinical team. At 4 week ...[more]
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