Patients With Reflux Esophagitis Possess a Possible Different Oral Microbiota Compared With Healthy Controls.

ABSTRACT:

Background and aim

Reflux Esophagitis (RE) is caused by a variety of factors including anatomical and functional alterations involved in the pathogenesis. Oral microbiota is influenced by many factors such as heredity, nutrition, environments and host conditions, but little is known about relationship between oral microbiota and RE. The aim of this study was to explore whether the oral microbiota is changed in patients with RE.

Methods

To clarify this correlation, fresh saliva samples from all subjects were collected and then oral microorganism diversity was analysed in 55 patients with RE and 51 controls via hypervariable tag sequencing and analyzing the V3-V4 region of the 16S rDNA gene.

Results

There was no difference found in oral microbial diversity betwee

SUBMITTER: Wang B 

PROVIDER: S-EPMC7358540 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature