Bioactive amorphous magnesium phosphate-polyetheretherketone composite filaments for 3D printing.

ABSTRACT:

Objective

The aim of this study was to develop bioactive and osseointegrable polyetheretherketone (PEEK)-based composite filaments melt-blended with novel amorphous magnesium phosphate (AMP) particles for 3D printing of dental and orthopedic implants.

Materials and methods

A series of materials and biological analyses of AMP-PEEK were performed. Thermal stability, thermogravimetric and differential scanning calorimetry curves of as-synthesized AMP were measured. Complex viscosity, elastic modulus and viscous modulus were determined using a rotational rheometer. In vitro bioactivity was analyzed using SBF immersion method. SEM, EDS and XRD were used to study the apatite-forming ability of the AMP-PEEK filaments. Mouse pre-osteoblasts (MC3T3-E1) were cultured and analyzed for

SUBMITTER: Sikder P 

PROVIDER: S-EPMC7359049 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature