FDG PET versus CT radiomics to predict outcome in malignant pleural mesothelioma patients.

ABSTRACT:

Background

Careful selection of malignant pleural mesothelioma (MPM) patients for curative treatment is of highest importance, as the multimodal treatment regimen is challenging for patients and harbors a high risk of substantial toxicity. Radiomics-a quantitative method for image analysis-has shown its prognostic ability in different tumor entities and could therefore play an important role in optimizing patient selection for radical cancer treatment. So far, radiomics as a prognostic tool in MPM was not investigated.

Materials and methods

This study is based on 72 MPM patients treated with surgery in a curative intent at our institution between 2009 and 2017. Pre-treatment Fluorine-18 fluorodeoxyglucose (FDG) PET and CT scans were used for radiomics outcome modeling. After

SUBMITTER: Pavic M 

PROVIDER: S-EPMC7359199 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature