Memory Deficits Precede Increases in Depressive Symptoms in Later Adulthood.

ABSTRACT: OBJECTIVES:We examined bidirectional, time-ordered associations between age-related changes in depressive symptoms and memory. METHOD:Data came from 107,599 community-dwelling adults, aged 49-90 years, who participated in the Survey of Health, Ageing, and Retirement in Europe (SHARE). Depressive symptoms were measured with the EURO-D inventory, and memory was evaluated as delayed recall of a 10-word list. Participants were assessed up to five times at 2-year intervals. Dynamic structural equation models were used to estimate longitudinal and time-ordered (lead-lag) relations between depressive symptoms and memory performance. RESULTS:Depressive symptoms increased and memory scores decreased across the observed age range, with worsening mostly evident after age 62 years. These long-term cha

SUBMITTER: Aichele S 

PROVIDER: S-EPMC7359446 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature