Small intestinal microbiota composition and the prognosis of infants with ileostomy resulting from distinct primary diseases.

ABSTRACT:

Background

Studies of microbiota composition of infants with small intestinal ostomy due to various etiologies are limited. Here, we characterized the intestinal microbiota of neonates with ileostomy resulting from distinct primary diseases.

Methods

Fifteen patients with necrotizing enterocolitis, eight patients with meconium peritonitis, and seven patients with Hirschsprung's disease were included in the study. The small intestinal microbiota composition in infants with ileostomy caused by these diseases was studied.

Results

Microbial diversity in neonatal ileostomy fluid was generally low, and was dominated by members of the Proteobacteria and Firmicutes phyla. At the genus level, the most abundant were Klebsiella, Escherichia-Shigella, Streptococcus, Clostridium se

SUBMITTER: Qian T 

PROVIDER: S-EPMC7359560 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature