Laboratory colonization by Dirofilaria immitis alters the microbiome of female Aedes aegypti mosquitoes.

ABSTRACT:

Background

The ability of blood-feeding arthropods to successfully acquire and transmit pathogens of medical and veterinary importance has been shown to be interfered with, or enhanced by, the arthropod's native microbiome. Mosquitoes transmit viruses, protozoan and filarial nematodes, the majority of which contribute to the 17% of infectious disease cases worldwide. Dirofilaria immitis, a mosquito-transmitted filarial nematodes of dogs and cats, is vectored by several mosquito species including Aedes aegypti.

Methods

In this study, we investigated the impact of D. immitis colonization on the microbiome of laboratory reared female Ae. aegypti. Metagenomic analysis of the V3-V4 variable region of the microbial 16S RNA gene was used for identification of the microbial differen

SUBMITTER: Adegoke A 

PROVIDER: S-EPMC7359625 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature