An Analysis of Anesthesia Induction Dosing in Female Older Adults.

ABSTRACT:

Background/objectives

In the context of an aging surgical population, appropriate anesthetic induction dose adjustments for the older adult remain poorly defined. In the present study, we describe the prevalence of excess induction agent dose in reference to US Food and Drug Administration (FDA) guidance and seek to investigate the possible association of such excess dose with postinduction hypotension and postoperative acute kidney injury (AKI).

Study design

A retrospective observational study was conducted in a large tertiary teaching hospital in accordance with our a priori analytic protocol as registered on ClinicalTrials.gov (NCT03699696). For inclusion, patients had to be 65 years or older and to have received general anesthesia with propofol induction for gynecologic

SUBMITTER: Chen EY 

PROVIDER: S-EPMC7359723 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature