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PiVR: An affordable and versatile closed-loop platform to study unrestrained sensorimotor behavior.


ABSTRACT: Tools enabling closed-loop experiments are crucial to delineate causal relationships between the activity of genetically labeled neurons and specific behaviors. We developed the Raspberry Pi Virtual Reality (PiVR) system to conduct closed-loop optogenetic stimulation of neural functions in unrestrained animals. PiVR is an experimental platform that operates at high temporal resolution (70 Hz) with low latencies (<30 milliseconds), while being affordable (

SUBMITTER: Tadres D 

PROVIDER: S-EPMC7360024 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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PiVR: An affordable and versatile closed-loop platform to study unrestrained sensorimotor behavior.

Tadres David D   Louis Matthieu M  

PLoS biology 20200714 7


Tools enabling closed-loop experiments are crucial to delineate causal relationships between the activity of genetically labeled neurons and specific behaviors. We developed the Raspberry Pi Virtual Reality (PiVR) system to conduct closed-loop optogenetic stimulation of neural functions in unrestrained animals. PiVR is an experimental platform that operates at high temporal resolution (70 Hz) with low latencies (<30 milliseconds), while being affordable (<US$500) and easy to build (<6 hours). Th  ...[more]

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