Real-world effectiveness of osteoporosis treatment in the oldest old.

ABSTRACT: We studied effectiveness of osteoporosis treatment in women older than 80 years, who often are not included in clinical trials. Treatments were as effective on bone density and fractures as in younger women.

Introduction

To study real-world effectiveness of osteoporosis treatment on BMD and fractures in the oldest old women (≥ 80 years) compared with women (60-79 years) in the clinical setting using Swedish health register data.

Methods

National registers and data from DXA machines were used to study effectiveness of all available osteoporosis treatments in women 60-79 and ≥ 80 years using three approaches: (1) Total Hip BMD change up to 8 years after treatment start; (2) fracture incidence where patients served as their own controls, comparing the first 3 months after treatm

SUBMITTER: Strom O 

PROVIDER: S-EPMC7360659 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature