Safety of Plasma Infusions in Parkinson's Disease.

ABSTRACT:

Background

Young plasma infusions have emerged as a potential treatment for neurodegenerative disease, and convalescent plasma therapy has been used safely in the management of viral pandemics. However, the effect of plasma therapy in Parkinson's disease (PD) is unknown.

Objectives

The objective of this study was to determine the safety, tolerability, and feasibility of plasma infusions in people with PD.

Methods

A total of 15 people with clinically established PD, at least 1 cognitive complaint, and on stable therapy received 1 unit of young fresh frozen plasma twice a week for 4 weeks. Assessments and adverse effects were performed/reported on and off therapy at baseline, immediately after, and 4 weeks after the infusions ended. Adverse effects were also assessed du

SUBMITTER: Parker JE 

PROVIDER: S-EPMC7361360 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature