Liver involvement is not associated with mortality: results from a large cohort of SARS-CoV-2-positive patients.

ABSTRACT:

Background

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is frequently associated with liver test abnormalities.

Aims

To describe the evolution of liver involvement during SARS-CoV-2 infection and its effect on clinical course and mortality.

Methods

Data of 515 SARS-CoV-2-positive patients were collected at baseline and during follow-up, last evaluation or death. Stratification based on need for hospitalisation, severe disease and admission to intensive care unit (ICU) was performed. The association between liver test abnormalities (baseline and peak values) and ICU admission or death was also explored.

Results

Liver test abnormalities were found in 161 (31.3%) patients. Aspartate aminotransferase (AST), alanine aminotransferase (ALT) a

SUBMITTER: Ponziani FR 

PROVIDER: S-EPMC7361563 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature