Lung function in men with and without HIV.

ABSTRACT:

Objectives

Initial studies suggest HIV-positive persons may be at increased risk for chronic lung diseases such as chronic obstructive pulmonary disease, but have commonly relied on single-center designs, lacked HIV-negative controls, or assessed lung function with only spirometry. We tested differences in spirometry and single-breath diffusing capacity for carbon monoxide (DLCO) in persons with and without HIV.

Design

Cross-sectional, observational study.

Methods

Participants were enrolled from the Multicenter AIDS Cohort Study, a longitudinal cohort study of men who have sex with men (both HIV-positive and HIV-negative) at four sites in the United States. Standardized spirometry and DLCO testing were performed in all eligible, consenting participants at routine stud

SUBMITTER: Kunisaki KM 

PROVIDER: S-EPMC7362901 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature