Physical activity impacts insulin sensitivity post metabolic bariatric surgery in adolescents with severe obesity.

ABSTRACT:

Background/objectives

We hypothesized that physical activity (PA) improves insulin sensitivity in adolescents with severe obesity beyond that attributable to metabolic bariatric surgery (MBS).

Subjects/methods

StepWatch^TM monitors objectively measured PA in 88 participants in the Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study. Primary outcomes included absolute change in fasting insulin, HOMA-IR, and fasting glucose from pre-surgery (baseline) to 6, 12, 24, and 36 months post-MBS. SAS PROC TRAJ generated activity trajectories based on probability and individual participant step count trajectories. Linear regression models were used, adjusted for baseline value, visit, surgical procedure, sex, and percent change in BMI. Additional models adjust

SUBMITTER: Price PH 

PROVIDER: S-EPMC7363050 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature