Dioxin exposure and breast cancer risk in a prospective cohort study.

ABSTRACT:

Background

Dioxins are persistent organic pollutants generated from industrial combustion processes such as waste incineration. To date, results from epidemiologic studies of dioxin exposure and breast cancer risk have been mixed.

Objectives

To prospectively examine the association between ambient dioxin exposure using a nationwide spatial database of industrial dioxin-emitting facilities and invasive breast cancer risk in the Nurses' Health Study II (NHSII).

Methods

NHSII includes female registered nurses in the US who have completed self-administered biennial questionnaires since 1989. Incident invasive breast cancer diagnoses were self-reported and confirmed by medical record review. Dioxin exposure was estimated based on residential proximity, duration of residenc

SUBMITTER: VoPham T 

PROVIDER: S-EPMC7363533 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature