Urinary levels of environmental phenols and parabens and antioxidant enzyme activity in the blood of women.

ABSTRACT:

Background

The balance between oxidative stress and antioxidant enzymes is one biological mechanism by which environmental and lifestyle exposures affect health outcomes. Yet, no studies have examined the relationship between environmental phenolic compounds and parabens or their mixtures in relation to antioxidant enzyme activity in women of reproductive age.

Methods

Sixteen environmental phenols and parabens were measured in urine 2-5 times across two months of follow-up in 143 women aged 18-44 years. Four antioxidant enzymes, erythrocyte and plasma glutathione peroxidase (eGPx, pGPx), glutathione reductase (GSHR), superoxide dismutase (SOD) were measured in plasma. Linear mixed models were adjusted for age, body mass index, race, and creatinine and were weighted with inve

SUBMITTER: Pollack AZ 

PROVIDER: S-EPMC7363544 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature