Methacrylamide-methacrylate hybrid monomers for dental applications.

ABSTRACT:

Objectives

The susceptibility of methacrylates to hydrolytic and enzymatic degradation may be a contributing factor limiting the clinical lifespan of resin composite restorations. The elimination of labile ester bonds is a potential advantage of methacrylamides, which have been shown to produce more stable restorative interfaces. The rationale of this study is to design hydrolytically and enzymatically stable adhesive monomers, with the added benefit of being able to form crosslinked networks. The objective of this study was to synthesize difunctional, hybrid methacrylate-methacrylamide monomers, and evaluate them as potential monomers for dental adhesives.

Materials and methods

HEMA, TEGDMA (controls) or secondary methacrylamides (HEMAM - commercially available, 2EM and 2dM

SUBMITTER: Fugolin AP 

PROVIDER: S-EPMC7363560 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature