Complete genome sequences of Streptococcus pyogenes type strain reveal 100%-match between PacBio-solo and Illumina-Oxford Nanopore hybrid assemblies.

ABSTRACT: We present the first complete, closed genome sequences of Streptococcus pyogenes strains NCTC 8198^T and CCUG 4207^T, the type strain of the type species of the genus Streptococcus and an important human pathogen that causes a wide range of infectious diseases. S. pyogenes NCTC 8198^T and CCUG 4207^T are derived from deposit of the same strain at two different culture collections. NCTC 8198^T was sequenced, using a PacBio platform; the genome sequence was assembled de novo, using HGAP. CCUG 4207^T was sequenced and a de novo hybrid assembly was generated, using SPAdes, combining Illumina and Oxford Nanopore sequence reads. Both strategies yielded closed genome sequences of 1,914,862 bp, identical in length and sequence identity. C

SUBMITTER: Salva-Serra F 

PROVIDER: S-EPMC7363880 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature