Ovarian cancer: diagnostic accuracy and tumor types distribution in East Africa compared to North America.

ABSTRACT:

Background

Ovarian cancer is a spectrum of several histologically distinct tumor types that differ in etiology, response to therapy, and prognosis. In resource-limited settings, the diagnosis of ovarian cancer can be challenging. This study describes the distribution of ovarian cancer tumor types in East Africa as well as assessing the diagnostic accuracy by using contemporary methods.

Methods

Data from 210 women identified from the records with a diagnosis of ovarian cancer in a period of 15 years were included. Two tissue microarrays were constructed and stained with 20 antibodies relevant to ovarian cancer subtyping. An integrated diagnosis was reached by the review of full Haematoxylin and Eosin stained sections, with consideration of immunohistochemical results. The int

SUBMITTER: Rambau PF 

PROVIDER: S-EPMC7364467 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature