Advanced organ support (ADVOS) in the critically ill: first clinical experience in patients with multiple organ failure.

ABSTRACT:

Background

Prevalence of multiple organ failure (MOF) in critically ill patients is increasing and associated mortality remains high. Extracorporeal organ support is a cornerstone in the management of MOF. We report data of an advanced hemodialysis system based on albumin dialysis (ADVOS multi device) that can regulate acid-base balance in addition to the established properties of renal replacement therapy and albumin dialysis systems in critically ill patients with MOF.

Methods

34 critically ill patients with MOF received 102 ADVOS treatment sessions in the Department of Intensive Care Medicine of the University Medical Center Hamburg-Eppendorf. Markers of metabolic detoxification and acid-base regulation were collected and blood gas analyses were performed. A subgroup anal

SUBMITTER: Fuhrmann V 

PROVIDER: S-EPMC7364697 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature