Distinct association between cerebral arterial pulsatility and subtypes of cerebral small vessel disease.

ABSTRACT:

Background

Increased arterial resistance is a potential pathological mechanism of cerebral small vessel disease (cSVD).

Aim

In this study, we aimed to investigate the association between pulsatility index (PI) representing cerebral arterial resistance and subtypes of cSVD in patients with lacunar stroke.

Methods

We included consecutive lacunar stroke patients between 2010 and 2013. White matter hyperintensity (WMH) volume was rated using semi-automated quantitative methods. Additionally, the presence of old lacunar infarct (OLI), cerebral microbleed (CMB), or enlarged perivascular space (EPVS) was also evaluated. The relationship between PI, measured in each middle cerebral artery, and the subtype/burden of cSVD was analyzed in the relevant hemisphere.

Results

SUBMITTER: Nam KW 

PROVIDER: S-EPMC7365409 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature