Association of blood pressure with knee cartilage composition and structural knee abnormalities: data from the osteoarthritis initiative.

ABSTRACT:

Objective

To investigate the associations of systolic blood pressure (SBP) and diastolic blood pressure (DBP) with changes in knee cartilage composition and joint structure over 48 months, using magnetic resonance imaging (MRI) data from the Osteoarthritis Initiative (OAI).

Materials and methods

A total of 1126 participants with right knee Kellgren-Lawrence (KL) score 0-2 at baseline, no history of rheumatoid arthritis, blood pressure measurements at baseline, and cartilage T2 measurements at baseline and 48 months were selected from the OAI. Cartilage composition was assessed using MRI T2 measurements, including laminar and gray-level co-occurrence matrix texture analyses. Structural knee abnormalities were graded using the whole-organ magnetic resonance imaging score (WORM

SUBMITTER: Ashmeik W 

PROVIDER: S-EPMC7365750 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature