Effect of Cold Atmospheric Plasma Therapy vs Standard Therapy Placebo on Wound Healing in Patients With Diabetic Foot Ulcers: A Randomized Clinical Trial.

ABSTRACT:

Importance

Diabetic foot ulcers are a common complication of diabetes and require specialized treatment. Cold atmospheric plasma (CAP) has been associated with benefits in wound infection and healing in previous smaller series of case reports. Yet the effect of CAP compared with standard care therapy in wound healing in diabetic foot ulcers remains to be studied.

Objective

To determine whether the application of CAP accelerates wound healing in diabetic foot ulcers compared with standard care therapy.

Design, setting, and participants

A prospective, randomized, placebo-controlled, patient-blinded clinical trial was conducted at 2 clinics with recruitment from August 17, 2016, to April 20, 2019. Patients were scheduled to remain in follow-up until April 30, 2024. Patie

SUBMITTER: Stratmann B 

PROVIDER: S-EPMC7366186 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature