Effects of Yersinia ruckeri invasion on the proteome of the Chinook salmon cell line CHSE-214

ABSTRACT: Yersinia ruckeri is an important bacterial pathogen of fish, in particular salmonids, it has been associated with systemic infections worldwide and, like many enteric bacteria, it is a facultative intracellular pathogen. However, the effect of Y. ruckeri’s interactions with the host at the cellular level have received little investigation. In the present study, a culture of Chinook Salmon Embryo (CHSE) cell line was exposed to Y. ruckeri. Afterwards, the proteins were investigated and identified by mass spectrometry and compared to the content of unexposed cultures. The results of this comparison showed that 4.7% of the identified proteins were found at significantly altered concentrations following infection. Interestingly, infection with Y. ruckeri was associated with significant changes

SUBMITTER: Menanteau-Ledouble S 

PROVIDER: S-EPMC7366648 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature