Individually customized transcranial temporal interference stimulation for focused modulation of deep brain structures: a simulation study with different head models.

ABSTRACT: Temporal interference (TI) stimulation was recently proposed that allows for the stimulation of deep brain structures with neocortical regions being minimally stimulated. For human brain modulation, TI current patterns are known to be considerably affected by the complex structures of the human head, and thus, it is hard to deliver TI current to a specific deep brain region. In this study, we optimized scalp electrode configurations and injection currents that can deliver maximum TI stimulation currents to a specific deep brain region, the head of the right hippocampus in this study, considering the real anatomical head structures of each individual. Three realistic finite element (FE) head models were employed for the optimization of TI stimulation. To generate TI current patterns, two pa

SUBMITTER: Lee S 

PROVIDER: S-EPMC7366675 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature