Early Bacterial Colonization and Antibiotic Resistance Gene Acquisition in Newborns.

ABSTRACT: Several studies have recently identified the main factors contributing to the bacterial colonization of newborns and the dynamics of the infant microbiome development. However, most of these studies address large time periods of weeks or months after birth, thereby missing on important aspects of the early microbiome maturation, such as the acquisition of antibiotic resistance determinants during postpartum hospitalization. The pioneer bacterial colonization and the extent of its associated antibiotic resistance gene (ARG) dissemination during this early phase of life are largely unknown. Studies addressing resistant bacteria or ARGs in neonates often focus only on the presence of particular bacteria or genes from a specific group of antibiotics. In the present study, we investigated the g

SUBMITTER: Klassert TE 

PROVIDER: S-EPMC7366792 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature