Ontology highlight
ABSTRACT:
SUBMITTER: Yadav RP
PROVIDER: S-EPMC7367195 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Yadav Ram Prakash RP Mäkelä Juho-Antti JA Hyssälä Hanna H Cisneros-Montalvo Sheyla S Kotaja Noora N
Nucleic acids research 20200701 13
Constitutive heterochromatin at the pericentric regions of chromosomes undergoes dynamic changes in its epigenetic and spatial organization during spermatogenesis. Accurate control of pericentric heterochromatin is required for meiotic cell divisions and production of fertile and epigenetically intact spermatozoa. In this study, we demonstrate that pericentric heterochromatin is expressed during mouse spermatogenesis to produce major satellite repeat (MSR) transcripts. We show that the endonucle ...[more]